The lineage-specific, intrinsically disordered N-terminal extension of monothiol glutaredoxin 1 from trypanosomes contains a regulatory region

The lineage-specific, intrinsically disordered N-terminal extension of monothiol glutaredoxin 1 from trypanosomes contains a regulatory region

Abstract Glutaredoxins (Grx) are small proteins conserved throughout all the kingdoms of life that are engaged in a wide variety of biological processes and share a common thioredoxin-fold. Among them, class II Grx are redox-inactive proteins involved in iron-sulfur (FeS) metabolism. They contain a...

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Bibliographic Details
Main Authors: Mattia Sturlese, Bruno Manta, Andrea Bertarello, Mariana Bonilla, Moreno Lelli, Barbara Zambelli, Karin Grunberg, Stefano Mammi, Marcelo A. Comini, Massimo Bellanda
Format: Article
Language:English
Published: Nature Publishing Group 2018-09-01
Series:Scientific Reports
Subjects:
Grx C1
Intrinsically Disordered Regions
Residual Dipolar Couplings (RDCs)
Multiangle Light Scattering (MALS)
Limited Proteolysis Assays
Online Access:https://doi.org/10.1038/s41598-018-31817-4

Internet

https://doi.org/10.1038/s41598-018-31817-4

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