Prospective evaluation of NGS-based liquid biopsy in untreated late stage non-squamous lung carcinoma in a single institution

Prospective evaluation of NGS-based liquid biopsy in untreated late stage non-squamous lung carcinoma in a single institution

Abstract Background NGS from plasma samples in non-squamous cell lung carcinoma (NSCC) can aid in the detection of actionable genomic alterations. However, the absolute clinical value of NGS in liquid biopsy (LB) made at baseline is currently uncertain. We assessed the impact of plasma-based NGS usi...

Full description

Bibliographic Details
Main Authors: Simon Heeke, Véronique Hofman, Marius Ilié, Maryline Allegra, Virginie Lespinet, Olivier Bordone, Jonathan Benzaquen, Jacques Boutros, Michel Poudenx, Salomé Lalvée, Virginie Tanga, Carole Salacroup, Christelle Bonnetaud, Charles-Hugo Marquette, Paul Hofman
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Journal of Translational Medicine
Subjects:
Liquid biopsy
Non-small cell lung carcinoma
NGS
Driver genomic alterations
cfDNA
Online Access:http://link.springer.com/article/10.1186/s12967-020-02259-2

Internet

http://link.springer.com/article/10.1186/s12967-020-02259-2

Similar Items