Intracellular persistence of Staphylococcus aureus in endothelial cells is promoted by the absence of phenol-soluble modulins

Intracellular persistence of Staphylococcus aureus in endothelial cells is promoted by the absence of phenol-soluble modulins

A large proportion of clinical S. aureus isolates that carry an inactive Agr system are associated with persistent infection that is difficult to treat. Once S. aureus is inside the bloodstream, it can cross the endothelial barrier and invade almost every organ in the human body. Endothelial cells c...

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Bibliographic Details
Main Authors: Anke Siegmund, Muhammad Awais Afzal, Felix Tetzlaff, Daniela Keinhörster, Fabio Gratani, Kerstin Paprotka, Martin Westermann, Sandor Nietzsche, Christiane Wolz, Martin Fraunholz, Christian A. Hübner, Bettina Löffler, Lorena Tuchscherr
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Virulence
Subjects:
staphylococcus aureus
intracellular persistence
phenol-soluble modulins
lc3-vesicles
chronic infections
Online Access:http://dx.doi.org/10.1080/21505594.2021.1910455

Internet

http://dx.doi.org/10.1080/21505594.2021.1910455

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