Relationships between Substrate Promiscuity and Chiral Selectivity of Esterases from Phylogenetically and Environmentally Diverse Microorganisms

Relationships between Substrate Promiscuity and Chiral Selectivity of Esterases from Phylogenetically and Environmentally Diverse Microorganisms

Substrate specificity and selectivity of a biocatalyst are determined by the protein sequence and structure of its active site. Finding versatile biocatalysts acting against multiple substrates while at the same time being chiral selective is of interest for the pharmaceutical and chemical industry....

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Bibliographic Details
Main Authors: Cristina Coscolín, Mónica Martínez-Martínez, Jennifer Chow, Rafael Bargiela, Antonio García-Moyano, Gro E. K. Bjerga, Alexander Bollinger, Runar Stokke, Ida H. Steen, Olga V. Golyshina, Michail M. Yakimov, Karl-Erich Jaeger, Alexander F. Yakunin, Wolfgang R. Streit, Peter N. Golyshin, Manuel Ferrer
Format: Article
Language:English
Published: MDPI AG 2018-01-01
Series:Catalysts
Subjects:
esterase
metagenomics
promiscuity
selectivity
Online Access:http://www.mdpi.com/2073-4344/8/1/10

Internet

http://www.mdpi.com/2073-4344/8/1/10

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