Analysis of Epithelial Growth Factor-Receptor (EGFR) Phosphorylation in Uterine Smooth Muscle Tumors: Correlation to Mucin-1 and Galectin-3 Expression

Analysis of Epithelial Growth Factor-Receptor (EGFR) Phosphorylation in Uterine Smooth Muscle Tumors: Correlation to Mucin-1 and Galectin-3 Expression

Uterine fibroids are the commonest uterine benign tumors. A potential mechanism of malignant transformation from leiomyomas to leiomyosarcomas has been described. Tyrosine phosphorylation is a key mechanism that controls biological functions, such as proliferation and cell differentiation. The aim o...

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Bibliographic Details
Main Authors: Udo Jeschke, Klaus Friese, Nina Ditsch, Doris Mayr, Antonis Makrigiannakis, Thomas Vrekoussis, David Roeder, Tobias Weissenbacher, Darius Dian
Format: Article
Language:English
Published: MDPI AG 2013-02-01
Series:International Journal of Molecular Sciences
Subjects:
myometrium
leiomyoma
leiomyosarcoma
phosphorylation
EGFR
tyrosine kinase
Online Access:http://www.mdpi.com/1422-0067/14/3/4783

Internet

http://www.mdpi.com/1422-0067/14/3/4783

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