Integrated data analysis reveals potential drivers and pathways disrupted by DNA methylation in papillary thyroid carcinomas

Integrated data analysis reveals potential drivers and pathways disrupted by DNA methylation in papillary thyroid carcinomas

Abstract Background Papillary thyroid carcinoma (PTC) is a common endocrine neoplasm with a recent increase in incidence in many countries. Although PTC has been explored by gene expression and DNA methylation studies, the regulatory mechanisms of the methylation on the gene expression was poorly cl...

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Bibliographic Details
Main Authors: Caroline Moraes Beltrami, Mariana Bisarro dos Reis, Mateus Camargo Barros-Filho, Fabio Albuquerque Marchi, Hellen Kuasne, Clóvis Antônio Lopes Pinto, Srikant Ambatipudi, Zdenko Herceg, Luiz Paulo Kowalski, Silvia Regina Rogatto
Format: Article
Language:English
Published: BMC 2017-05-01
Series:Clinical Epigenetics
Subjects:
Papillary thyroid cancer
DNA methylation
Integrative analysis
FGF signaling pathway
Retinoic acid pathway
BRAFV600E mutation
Online Access:http://link.springer.com/article/10.1186/s13148-017-0346-2

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http://link.springer.com/article/10.1186/s13148-017-0346-2

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