Quantitative investigation of the direct interaction between Hemagglutinin and fusion proteins of Peste des petits ruminant virus using surface Plasmon resonance

Abstract Background The specific and dynamic interaction between the hemagglutinin (H) and fusion (F) proteins of morbilliviruses is a prerequisite for the conformational rearrangements and membrane fusion during infection process. The two heptad repeat regions (HRA and HRB) of F protein are both im...

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Bibliographic Details
Main Authors: Xuelian Meng, Ruixue Deng, Xueliang Zhu, Zhidong Zhang
Format: Article
Language:English
Published: BMC 2018-01-01
Series:Virology Journal
Subjects:
SPR
Online Access:http://link.springer.com/article/10.1186/s12985-018-0933-7