Comparison of Modified Chandler, Roller Pump, and Ball Valve Circulation Models for In Vitro Testing in High Blood Flow Conditions: Application in Thrombogenicity Testing of Different Materials for Vascular Applications

Three different models, a modified Chandler loop, roller pump, and a new ball valve model (Hemobile), were compared with regard to intrinsic damage of blood components and activation of platelets. The Hemobile was used for testing of polymer tubes. High flow was not possible with the Chandler loop....

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Bibliographic Details
Main Authors: Wim van Oeveren, Ignace F. Tielliu, Jurgen de Hart
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:International Journal of Biomaterials
Online Access:http://dx.doi.org/10.1155/2012/673163