SELDI-TOF-MS ProteinChip array profiling of T-cell clones propagated in long-term culture identifies human profilin-1 as a potential bio-marker of immunosenescence

<p>Abstract</p> <p>Background</p> <p>The adaptive immune response requires waves of T-cell clonal expansion on contact with pathogen and elimination after clearance of the source of antigen. However, lifelong persistent infections with common viruses cause chronic antig...

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Bibliographic Details
Main Authors: Longdin Robin, Pawelec Graham, Mazzatti Dawn J, Powell Jonathan R, Forsey Rosalyn J
Format: Article
Language:English
Published: BMC 2007-06-01
Series:Proteome Science
Online Access:http://www.proteomesci.com/content/5/1/7