SELDI-TOF-MS ProteinChip array profiling of T-cell clones propagated in long-term culture identifies human profilin-1 as a potential bio-marker of immunosenescence
<p>Abstract</p> <p>Background</p> <p>The adaptive immune response requires waves of T-cell clonal expansion on contact with pathogen and elimination after clearance of the source of antigen. However, lifelong persistent infections with common viruses cause chronic antig...
Main Authors: | Longdin Robin, Pawelec Graham, Mazzatti Dawn J, Powell Jonathan R, Forsey Rosalyn J |
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Format: | Article |
Language: | English |
Published: |
BMC
2007-06-01
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Series: | Proteome Science |
Online Access: | http://www.proteomesci.com/content/5/1/7 |
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