Immunobiology of Uveal Melanoma: State of the Art and Therapeutic Targets

Immunobiology of Uveal Melanoma: State of the Art and Therapeutic Targets

Uveal Melanoma (UM) represents the most common primary intraocular malignant tumor in adults. Although it originates from melanocytes as cutaneous melanoma, it shows significant clinical and biological differences with the latter, including high resistance to immune therapy. Indeed, UM can evade imm...

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Bibliographic Details
Main Authors: Maria Sofia Basile, Emanuela Mazzon, Paolo Fagone, Antonio Longo, Andrea Russo, Matteo Fallico, Vincenza Bonfiglio, Ferdinando Nicoletti, Teresio Avitabile, Michele Reibaldi
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Oncology
Subjects:
uveal melanoma
inhibitory checkpoints
immunotherapy
immune-escape
immune-privilege
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.01145/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2019.01145/full

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