Immunoglobulin G subclass switching impacts sensitivity of an immunoassay targeting Francisella tularensis lipopolysaccharide.

The CDC Tier 1 select agent Francisella tularensis is a small, Gram-negative bacterium and the causative agent of tularemia, a potentially life-threatening infection endemic in the United States, Europe and Asia. Currently, there is no licensed vaccine or rapid point-of-care diagnostic test for tula...

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Bibliographic Details
Main Authors: Teerapat Nualnoi, Adam Kirosingh, Kaitlin Basallo, Derrick Hau, Marcellene A Gates-Hollingsworth, Peter Thorkildson, Reva B Crump, Dana E Reed, Sujata Pandit, David P AuCoin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5890998?pdf=render