Towards Reassignment of the Methionine Codon AUG to Two Different Noncanonical Amino Acids in Bacterial Translation

Genetic encoding of noncanonical amino acids (ncAAs) through sense codon reassignment is an efficient tool for expanding the chemical functionality of proteins. Incorporation of multiple ncAAs, however, is particularly challenging. This work describes the first attempts to reassign the sense methion...

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Bibliographic Details
Main Authors: Alessandro De Simone, Carlos G. Acevedo-Rocha, Michael Georg Hoesl, Nediljko Budisa
Format: Article
Language:English
Published: Croatian Chemical Society 2016-06-01
Series:Croatica Chemica Acta
Online Access:http://hrcak.srce.hr/file/248152