Variation in loss of immunity shapes influenza epidemics and the impact of vaccination

Abstract Background Protective antibody immunity against the influenza A virus wanes in 2–7 years due to antigenic drift of the virus’ surface proteins. The duration of immune protection is highly variable because antigenic evolution of the virus is irregular. Currently, the variable nature of the d...

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Bibliographic Details
Main Authors: Rutger G. Woolthuis, Jacco Wallinga, Michiel van Boven
Format: Article
Language:English
Published: BMC 2017-09-01
Series:BMC Infectious Diseases
Online Access:http://link.springer.com/article/10.1186/s12879-017-2716-y