Inherited risk plus prenatal insult caused malignant dysfunction in mesenteric arteries in adolescent SHR offspring.

Prenatal hypoxia can induce cardiovascular diseases in the offspring. This study determined whether and how prenatal hypoxia may cause malignant hypertension and impaired vascular functions in spontaneous hypertension rat (SHR) offspring at adolescent stage. Pregnant SHR were placed in a hypoxic cha...

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Bibliographic Details
Main Authors: Yuan Zhong, Xueqin Feng, Ting Xu, Chunli Yang, Wenna Zhang, Xueyi Chen, Xiaorong Fan, Likui Lu, Meng Zhang, Lingjun Li, Zhice Xu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0215994