Generation of circularly permuted fluorescent-protein-based indicators for in vitro and in vivo detection of citrate.

Indicators for citrate, particularly those applicable to its in vivo detection and quantitation, have attracted much interest in both biochemical studies and industrial applications since citrate is a key metabolic intermediate playing important roles in living cells. We generated novel fluorescence...

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Bibliographic Details
Main Authors: Yuki Honda, Kohtaro Kirimura
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3661591?pdf=render