Neutral sphingomyelinase in physiological and measles virus induced T cell suppression.
T cell paralysis is a main feature of measles virus (MV) induced immunosuppression. MV contact mediated activation of sphingomyelinases was found to contribute to MV interference with T cell actin reorganization. The role of these enzymes in MV-induced inhibition of T cell activation remained equall...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-12-01
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Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC4270778?pdf=render |