C/EBPβ Promotes Immunity to Oral Candidiasis through Regulation of β-Defensins.

Humans or mice subjected to immunosuppression, such as corticosteroids or anti-cytokine biologic therapies, are susceptible to mucosal infections by the commensal fungus Candida albicans. Recently it has become evident that the Th17/IL-17 axis is essential for immunity to candidiasis, but the downst...

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Bibliographic Details
Main Authors: Michelle R Simpson-Abelson, Erin E Childs, M Carolina Ferreira, Shrinivas Bishu, Heather R Conti, Sarah L Gaffen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4552893?pdf=render