Synthesis of Nucleobase-Modified RNA Oligonucleotides by Post-Synthetic Approach
The chemical synthesis of modified oligoribonucleotides represents a powerful approach to study the structure, stability, and biological activity of RNAs. Selected RNA modifications have been proven to enhance the drug-like properties of RNA oligomers providing the oligonucleotide-based therapeutic...
Main Authors: | Karolina Bartosik, Katarzyna Debiec, Anna Czarnecka, Elzbieta Sochacka, Grazyna Leszczynska |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-07-01
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Series: | Molecules |
Subjects: | |
Online Access: | https://www.mdpi.com/1420-3049/25/15/3344 |
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