Sulforaphane potentiates RNA damage induced by different xenobiotics.

The isothiocyanate sulforaphane (SFN) possesses interesting anticancer activities. However, recent studies reported that SFN promotes the formation of reactive oxygen species (ROS) as well as DNA breakage.We investigated whether SFN is able to damage RNA, whose loss of integrity was demonstrated in...

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Bibliographic Details
Main Authors: Carmela Fimognari, Monia Lenzi, Piero Sestili, Eleonora Turrini, Lorenzo Ferruzzi, Patrizia Hrelia, Giorgio Cantelli-Forti
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3335137?pdf=render