Clinical Impact of Inherited and Acquired Genetic Variants in Mastocytosis

Clinical Impact of Inherited and Acquired Genetic Variants in Mastocytosis

Mastocytosis is a rare and complex disease characterized by expansion of clonal mast cells (MC) in skin and/or various internal organ systems. Involvement of internal organs leads to the diagnosis of systemic mastocytosis (SM). The WHO classification divides SM into indolent SM, smoldering SM and ad...

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Bibliographic Details
Main Authors: Boguslaw Nedoszytko, Michel Arock, Jonathan J. Lyons, Guillaume Bachelot, Lawrence B. Schwartz, Andreas Reiter, Mohamad Jawhar, Juliana Schwaab, Magdalena Lange, Georg Greiner, Gregor Hoermann, Marek Niedoszytko, Dean D. Metcalfe, Peter Valent
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:International Journal of Molecular Sciences
Subjects:
mast cells
mast cell activation syndrome
gene polymorphisms
prognostication
hereditary alpha-tryptasemia
<i>KIT</i> variants
Online Access:https://www.mdpi.com/1422-0067/22/1/411

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https://www.mdpi.com/1422-0067/22/1/411

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