Melatonin Improves Mitochondrial Dynamics and Function in the Kidney of Zücker Diabetic Fatty Rats

Melatonin Improves Mitochondrial Dynamics and Function in the Kidney of Zücker Diabetic Fatty Rats

Obesity and associated diabetes (diabesity) impair kidney mitochondrial dynamics by augmenting fission and diminishing fusion, which results in mitochondrial and renal dysfunction. Based on available evidence, the antioxidant activities of melatonin may improve impaired renal mitochondrial function...

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Bibliographic Details
Main Authors: Ahmad Agil, Meriem Chayah, Lucia Visiedo, Miguel Navarro-Alarcon, José Manuel Rodríguez Ferrer, Mohamed Tassi, Russel J. Reiter, Gumersindo Fernández-Vázquez
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Journal of Clinical Medicine
Subjects:
nephropathy
diabetes
obesity
melatonin
mitochondrial function/dynamic
fission/fusion
Online Access:https://www.mdpi.com/2077-0383/9/9/2916

Internet

https://www.mdpi.com/2077-0383/9/9/2916

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