SB216763, a selective small molecule inhibitor of glycogen synthase kinase-3, improves bleomycin-induced pulmonary fibrosis via activating autophagy
An excessive accumulation of extracellular matrix composed by insoluble collagen is the core pathogenic change of fibroproliferative diseases including pulmonary fibrosis. We recently found that autophagy, a self-catabolic process that maintains intracellular homeostasis, participates critically in...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2013-07-01
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| Series: | Acta Pharmaceutica Sinica B |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211383513000439 |