Investigating the antigen specificity of multiple sclerosis central nervous system-derived immunoglobulins

The central nervous system (CNS) of patients with multiple sclerosis (MS) is the site where disease pathology is evident. Damaged CNS tissue is commonly associated with immune cell infiltration. This infiltrate often includes B cells that are found in multiple locations throughout the CNS, including...

Full description

Bibliographic Details
Main Authors: Simon N Willis, Panos eStathopoulos, Anne eChastre, Shannon D. Compton, David A. Hafler, Kevin C O'Connor
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-11-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00600/full