A shape-adjusted ellipse approach corrects for varied axonal dispersion angles and myelination in primate nerve roots

Abstract Segmentation of axons in light and electron micrographs allows for quantitative high-resolution analysis of nervous tissues, but varied axonal dispersion angles result in over-estimates of fiber sizes. To overcome this technical challenge, we developed a novel shape-adjusted ellipse (SAE) d...

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Bibliographic Details
Main Authors: Petra M. Bartmeyer, Natalia P. Biscola, Leif A. Havton
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-82575-9