Staphylococcus aureus Coordinates Leukocidin Expression and Pathogenesis by Sensing Metabolic Fluxes via RpiRc

Staphylococcus aureus Coordinates Leukocidin Expression and Pathogenesis by Sensing Metabolic Fluxes via RpiRc

Staphylococcus aureus is a formidable human pathogen that uses secreted cytolytic factors to injure immune cells and promote infection of its host. Of these proteins, the bicomponent family of pore-forming leukocidins play critical roles in S. aureus pathogenesis. The regulatory mechanisms governing...

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Bibliographic Details
Main Authors: Divya Balasubramanian, Elizabeth A. Ohneck, Jessica Chapman, Andy Weiss, Min Kyung Kim, Tamara Reyes-Robles, Judy Zhong, Lindsey N. Shaw, Desmond S. Lun, Beatrix Ueberheide, Bo Shopsin, Victor J. Torres
Format: Article
Language:English
Published: American Society for Microbiology 2016-06-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/7/3/e00818-16

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http://mbio.asm.org/cgi/content/full/7/3/e00818-16

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