Knockdown of ubiquitin-specific peptidase 39 inhibited the growth of osteosarcoma cells and induced apoptosis in vitro

Knockdown of ubiquitin-specific peptidase 39 inhibited the growth of osteosarcoma cells and induced apoptosis in vitro

Abstract Background Ubiquitin specific peptidase 39 (USP39), an essential factor in the assembly of the mature spliceosome complex, has an aberrant expression in several cancer. However, its function and the corresponding mechanism on human osteosarcoma has not been fully explored yet. Methods The m...

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Bibliographic Details
Main Authors: Zhihua Gan, Kun Han, Shuchen Lin, Haiyan Hu, Zan Shen, Daliu Min
Format: Article
Language:English
Published: BMC 2017-04-01
Series:Biological Research
Subjects:
Cell cycle
Migration
Osteosarcoma
Proliferation
USP39
Online Access:http://link.springer.com/article/10.1186/s40659-017-0121-z

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http://link.springer.com/article/10.1186/s40659-017-0121-z

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