Impact of acyclovir use on survival of patients with ventilator-associated pneumonia and high load herpes simplex virus replication

Impact of acyclovir use on survival of patients with ventilator-associated pneumonia and high load herpes simplex virus replication

Abstract Background Herpes simplex virus (HSV) replication can be detected in the respiratory secretions of a high proportion of ventilated intensive care unit (ICU) patients. However, the clinical significance remains poorly defined. We investigated whether patients with ventilator-associated pneum...

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Bibliographic Details
Main Authors: Lukas Schuierer, Michael Gebhard, Hans-Georg Ruf, Ulrich Jaschinski, Thomas M. Berghaus, Michael Wittmann, Georg Braun, Dirk H. Busch, Reinhard Hoffmann
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Critical Care
Subjects:
Ventilator-associated pneumonia
Bronchoalveolar lavage fluid
Simplexvirus
Real-time polymerase chain reaction
Acyclovir
Online Access:https://doi.org/10.1186/s13054-019-2701-5

Internet

https://doi.org/10.1186/s13054-019-2701-5

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