Distinct functions of AKT isoforms in breast cancer: a comprehensive review

Abstract Background AKT, also known as protein kinase B, is a key element of the PI3K/AKT signaling pathway. Moreover, AKT regulates the hallmarks of cancer, e.g. tumor growth, survival and invasiveness of tumor cells. After AKT was discovered in the early 1990s, further studies revealed that there...

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Bibliographic Details
Main Authors: Nico Hinz, Manfred Jücker
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Cell Communication and Signaling
Subjects:
AKT
Online Access:http://link.springer.com/article/10.1186/s12964-019-0450-3