Review of the safety and efficacy of ustekinumab

Ustekinumab is a subcutaneously and intravenously administered fully human monoclonal immunoglobulin (IgG1) antibody targeting the interleukin (IL)-12/23 shared P40 subunit. The pivotal role of IL-12/23 inflammatory-mediated pathways is increasingly recognized in a plethora of immune-mediated inflam...

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Bibliographic Details
Main Authors: Ellen J. Scherl, Sheila Kumar, Ryan U. Warren
Format: Article
Language:English
Published: SAGE Publishing 2010-09-01
Series:Therapeutic Advances in Gastroenterology
Online Access:https://doi.org/10.1177/1756283X10374216