Review of the safety and efficacy of ustekinumab
Ustekinumab is a subcutaneously and intravenously administered fully human monoclonal immunoglobulin (IgG1) antibody targeting the interleukin (IL)-12/23 shared P40 subunit. The pivotal role of IL-12/23 inflammatory-mediated pathways is increasingly recognized in a plethora of immune-mediated inflam...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2010-09-01
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Series: | Therapeutic Advances in Gastroenterology |
Online Access: | https://doi.org/10.1177/1756283X10374216 |