Gene expression changes in spinal motoneurons of the SOD1G93A transgenic model for ALS after treatment with G-CSF.
ABSTRACTBackgroundAmyotrophic lateral sclerosis (ALS) is an incurable fatal motoneuron disease with a lifetime risk of approximately 1:400. It is characterized by progressive weakness, muscle wasting, and death ensuing 3-5 years after diagnosis. Granulocyte-colony stimulating factor (G-CSF) is a dru...
Main Authors: | Alexandre eHenriques, Stefan eKastner, Eva eChatzikonstantinou, Claudie ePitzer, Christian ePlaas, Friederike eKirsch, Oliver eWafzig, Krüger eCarola, Robert eSpoelgen, Jose-Luis eGonzalez De Aguilar, Norbert eGretz, Armin eSchneider |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2015-01-01
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Series: | Frontiers in Cellular Neuroscience |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00464/full |
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