Tamoxifen Suppresses the Immune Response to <i>Plasmodium berghei</i> ANKA and Exacerbates Symptomatology

Tamoxifen Suppresses the Immune Response to <i>Plasmodium berghei</i> ANKA and Exacerbates Symptomatology

Malaria is the most lethal parasitic disease in the world. Mortality and severity in symptoms are higher in men than women, suggesting that oestrogens, which are in higher concentration in females than in males, may regulate the immune response against malaria. Tamoxifen, a selective oestrogen recep...

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Bibliographic Details
Main Authors: Luis Antonio Cervantes-Candelas, Jesús Aguilar-Castro, Fidel Orlando Buendía-González, Omar Fernández-Rivera, Armando Cervantes-Sandoval, Jorge Morales-Montor, Martha Legorreta-Herrera
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Pathogens
Subjects:
malaria
<i>Plasmodium berghei</i> ANKA
tamoxifen
oestrogens
immune system
Online Access:https://www.mdpi.com/2076-0817/10/6/743

Internet

https://www.mdpi.com/2076-0817/10/6/743

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