Identification and characterization of B-cell epitopes in the DBL4ε domain of VAR2CSA.

Identification and characterization of B-cell epitopes in the DBL4ε domain of VAR2CSA.

Malaria during pregnancy in Plasmodium falciparum endemic regions is a major cause of mortality and severe morbidity. VAR2CSA is the parasite ligand responsible for sequestration of Plasmodium falciparum infected erythrocytes to the receptor chondroitin sulfate A (CSA) in the placenta and is the lea...

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Main Authors: Sisse B Ditlev, Morten A Nielsen, Mafalda Resende, Mette Ø Agerbæk, Vera V Pinto, Pernille H Andersen, Pamela Magistrado, John Lusingu, Madeleine Dahlbäck, Thor G Theander, Ali Salanti
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22970138/pdf/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22970138/pdf/?tool=EBI

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