Schistosoma mansoni: preclinical studies with 9-acridanone-hydrazones in Cebus monkeys experimentally infected Schistosoma mansoni: estudos pré-clínicos com 9-acridanona-hidrazonas em macacos Cebus experimentalmente infectados

Derivatives of acridine (9-Acridanone-hydrazones) were tested in Cebus monkeys experimentally infected with Schistosoma mansoni, at the dosages of 50, 25, and 12.5 mg/kg (p.o., single dose). At least, four compounds seemed to be very promising, promoting alterations in the oogram and reducing the wo...

Full description

Bibliographic Details
Main Authors: Paulo Marcos Zech Coelho, Leógenes Horácio Pereira
Format: Article
Language:English
Published: Universidade de São Paulo 1991-02-01
Series:Revista do Instituto de Medicina Tropical de São Paulo
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46651991000100010