Cooperative synthesis of dopamine by non-dopaminergic neurons as a compensatory mechanism in the striatum of mice with MPTP-induced Parkinsonism

Cooperative synthesis of dopamine by non-dopaminergic neurons as a compensatory mechanism in the striatum of mice with MPTP-induced Parkinsonism

Since the late 80s it has been repeatedly shown that besides dopaminergic neurons, the brain contains so-called monoenzymatic neurons possessing one of the enzymes of dopamine (DA) synthesis, tyrosine hydroxylase (TH) or aromatic l-amino acid decarboxylase (AADC). However, the data on the existence...

Full description

Bibliographic Details
Main Authors: Elena A. Kozina, Aleksandr R. Kim, Anna Y. Kurina, Michael V. Ugrumov
Format: Article
Language:English
Published: Elsevier 2017-02-01
Series:Neurobiology of Disease
Subjects:
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
Tyrosine hydroxylase
Aromatic l-amino acid decarboxylase
Nigrostriatal system
Parkinson's disease
Mice
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996116302868

Internet

http://www.sciencedirect.com/science/article/pii/S0969996116302868

Similar Items