Hyperhomocysteinemia Is Associated with Inflammation, Bone Resorption, Vitamin B12 and Folate Deficiency and MTHFR C677T Polymorphism in Postmenopausal Women with Decreased Bone Mineral Density

Hyperhomocysteinemia Is Associated with Inflammation, Bone Resorption, Vitamin B12 and Folate Deficiency and MTHFR C677T Polymorphism in Postmenopausal Women with Decreased Bone Mineral Density

Osteoporosis is an age-related bone disease, affecting mainly postmenopausal women, characterized by decreased bone mineral density (BMD) and consequent risk of fractures. Homocysteine (Hcy), a sulfur-aminoacid whose serum level is regulated by methylenetrahydrofolate reductase (MTHFR) activity and...

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Bibliographic Details
Main Authors: Massimo De Martinis, Maria Maddalena Sirufo, Cristina Nocelli, Lara Fontanella, Lia Ginaldi
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:International Journal of Environmental Research and Public Health
Subjects:
osteoporosis
hyperhomocysteinemia
inflammation
vitamin D
bone
vitamin B12
Online Access:https://www.mdpi.com/1660-4601/17/12/4260

Internet

https://www.mdpi.com/1660-4601/17/12/4260

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