IL28B alleles exert an additive dose effect when applied to HCV-HIV coinfected persons undergoing peginterferon and ribavirin therapy.

IL28B alleles exert an additive dose effect when applied to HCV-HIV coinfected persons undergoing peginterferon and ribavirin therapy.

BACKGROUND:Genetic studies have demonstrated a strong association between single nucleotide polymorphisms (SNPs) at IL28B and response to treatment with peginterferon (PEG) and ribavirin (RBV) in HCV monoinfected persons. We sought to test these associations in a prospective PEG / weight based ribav...

Full description

Bibliographic Details
Main Authors: Barham K Abu Dayyeh, Namrata Gupta, Kenneth E Sherman, Paul I W de Bakker, Raymond T Chung, Aids Clinical Trials Group A5178 Study Team
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3189209?pdf=render

Internet

http://europepmc.org/articles/PMC3189209?pdf=render

Similar Items