Antibody Binding to SARS-CoV-2 S Glycoprotein Correlates with but Does Not Predict Neutralization

Antibody Binding to SARS-CoV-2 S Glycoprotein Correlates with but Does Not Predict Neutralization

Convalescent plasma from SARS-CoV-2 infected individuals and monoclonal antibodies were shown to potently neutralize viral and pseudoviral particles carrying the S glycoprotein. However, a non-negligent proportion of plasma samples from infected individuals, as well as S-specific monoclonal antibodi...

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Bibliographic Details
Main Authors: Shilei Ding, Annemarie Laumaea, Mehdi Benlarbi, Guillaume Beaudoin-Bussières, Romain Gasser, Halima Medjahed, Marie Pancera, Leonidas Stamatatos, Andrew T. McGuire, Renée Bazin, Andrés Finzi
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Viruses
Subjects:
COVID-19
SARS-COV-2
convalescent plasma
ELISA
neutralization
virus capture assay
Online Access:https://www.mdpi.com/1999-4915/12/11/1214

Internet

https://www.mdpi.com/1999-4915/12/11/1214

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