Overexpression of the Small RNA PA0805.1 in Pseudomonas aeruginosa Modulates the Expression of a Large Set of Genes and Proteins, Resulting in Altered Motility, Cytotoxicity, and Tobramycin Resistance
P. aeruginosa is an opportunistic pathogen of humans. With roughly 10% of its genes encoding transcriptional regulators, and hundreds of small noncoding RNAs (sRNAs) interspersed throughout the genome, P. aeruginosa is able to fine-tune its response to adapt and survive in the host and resist antimi...
Main Authors: | Shannon R. Coleman, Maren L. Smith, Victor Spicer, Ying Lao, Neeloffer Mookherjee, Robert E. W. Hancock |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2020-05-01
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Series: | mSystems |
Subjects: | |
Online Access: | https://doi.org/10.1128/mSystems.00204-20 |
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