Inflammation Determines the Capacity of Allogenic Endothelial Cells to Regulate Human Treg Expansion
During allotransplantation, the endothelium acts as semi-professional antigen-presenting cells with the ability to activate proliferation and to promote differentiation of CD4+-T subsets. These abilities are dependent on the luminal expression of HLA class II antigens by microvascular endothelial ce...
Main Authors: | Amy Rachael Cross, Julien Lion, Karine Poussin, Denis Glotz, Nuala Mooney |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2021-07-01
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Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2021.666531/full |
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