NTNU intranasal naloxone trial (NINA-1) study protocol for a double-blind, double-dummy, non-inferiority randomised controlled trial comparing intranasal 1.4 mg to intramuscular 0.8 mg naloxone for prehospital use
Introduction Intranasal (IN) naloxone is widely used to treat opioid overdoses. The advantage of nasal administration compared with injection lies in its suitability for administration by lay people as it is needless. Approved formulations of nasal naloxone with bioavailability of approximately 50%...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMJ Publishing Group
2020-11-01
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Series: | BMJ Open |
Online Access: | https://bmjopen.bmj.com/content/10/11/e041556.full |