Harnessing region-specific neurovascular signaling to promote germinal matrix vessel maturation and hemorrhage prevention

Germinal matrix hemorrhage (GMH), affecting about 1 in 300 births, is a major perinatal disease with lifelong neurological consequences. Yet despite advances in neonatal medicine, there is no effective intervention. GMH is characterized by localized bleeding in the germinal matrix (GM), due to inher...

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Bibliographic Details
Main Authors: Devi Santhosh, Joe Sherman, Shafi Chowdhury, Zhen Huang
Format: Article
Language:English
Published: The Company of Biologists 2019-11-01
Series:Disease Models & Mechanisms
Subjects:
Online Access:http://dmm.biologists.org/content/12/11/dmm041228