Childhood pre-B cell acute lymphoblastic leukemia with translocation t(1;19)(q21.1;p13.3) and two additional chromosomal aberrations involving chromosomes 1, 6, and 13: a case report

Childhood pre-B cell acute lymphoblastic leukemia with translocation t(1;19)(q21.1;p13.3) and two additional chromosomal aberrations involving chromosomes 1, 6, and 13: a case report

Abstract Background The translocation t(1;19)(q23;p13), which results in the TCF3-PBX1 chimeric gene, is one of the most frequent rearrangements observed in B cell acute lymphoblastic leukemia. It appears in both adult and pediatric patients with B cell acute lymphoblastic leukemia at an overall fre...

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Bibliographic Details
Main Authors: Abdulsamad Wafa, Manar As’sad, Thomas Liehr, Abdulmunim Aljapawe, Walid Al Achkar
Format: Article
Language:English
Published: BMC 2017-04-01
Series:Journal of Medical Case Reports
Subjects:
Acute lymphoblastic leukemia (ALL)
t(1;19)
TCF3-PBX1
Cytogenetics
Fluorescence in situ hybridization (FISH)
Prognostic factors
Online Access:http://link.springer.com/article/10.1186/s13256-017-1251-1

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http://link.springer.com/article/10.1186/s13256-017-1251-1

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