Childhood pre-B cell acute lymphoblastic leukemia with translocation t(1;19)(q21.1;p13.3) and two additional chromosomal aberrations involving chromosomes 1, 6, and 13: a case report
Abstract Background The translocation t(1;19)(q23;p13), which results in the TCF3-PBX1 chimeric gene, is one of the most frequent rearrangements observed in B cell acute lymphoblastic leukemia. It appears in both adult and pediatric patients with B cell acute lymphoblastic leukemia at an overall fre...
Main Authors: | Abdulsamad Wafa, Manar As’sad, Thomas Liehr, Abdulmunim Aljapawe, Walid Al Achkar |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2017-04-01
|
Series: | Journal of Medical Case Reports |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13256-017-1251-1 |
Similar Items
-
Sites of instability in the human TCF3 (E2A) gene adopt G-quadruplex DNA structures in vitro
by: Jonathan David Williams, et al.
Published: (2015-05-01) -
TOWARDS A B-LYMPHOID MODEL OF E2A-PBX1-MEDIATED LEUKEMOGENESIS: EVALUATING THE IMPACT OF HEMATOPOIETIC CELL OF ORIGIN ON THE TRANSFORMATION PROPERTIES OF A LEUKEMOGENIC TRANSCRIPTION FACTOR
by: Woodcroft, MARK
Published: (2013) -
Interpreting ‘Torah’ in Psalm 1 in the light of Psalm 119
by: Philippus J. Botha
Published: (2012-11-01) -
Interpreting ‘Torah’ in Psalm 1 in the light of Psalm 119
by: Philippus J. Botha
Published: (2012-11-01) -
Biclonal myelodysplastic syndrome involving six chromosomes and monoallelic loss of RB1 - A rare case
by: Klein Elisabeth, et al.
Published: (2011-08-01)