Pharmacological effects of fibroblast growth factor 21 are sex-specific in mice with the <em>lethal yellow</em> (A<sup>y</sup>) mutation
Hypothalamic melanocortin 4 receptors (MC4R) regulate energy balance. Mutations in the MC4R gene are the most common cause of monogenic obesity in humans. Fibroblast growth factor 21 (FGF21) is a promising antiobesity agent, but its effects on melanocortin obesity are unknown. Sex is an important bi...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Institute of Cytology and Genetics of Siberian Branch of the Russian Academy of Sciences
2020-04-01
|
| Series: | Vavilovskij Žurnal Genetiki i Selekcii |
| Subjects: | |
| Online Access: | https://vavilov.elpub.ru/jour/article/view/2424 |