A Model of Evolutionary Selection: The Cardiovascular Protective Function of the Longevity Associated Variant of BPIFB4

A Model of Evolutionary Selection: The Cardiovascular Protective Function of the Longevity Associated Variant of BPIFB4

Evolutionary forces select genetic variants that allow adaptation to environmental stresses. The genomes of centenarian populations could recapitulate the evolutionary adaptation model and reveal the secrets of disease resistance shown by these individuals. Indeed, longevity phenotype is supposed to...

Full description

Bibliographic Details
Main Authors: Francesco Villa, Albino Carrizzo, Anna Ferrario, Anna Maciag, Monica Cattaneo, Chiara Carmela Spinelli, Francesco Montella, Antonio Damato, Elena Ciaglia, Annibale Alessandro Puca
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:International Journal of Molecular Sciences
Subjects:
BPIFB4
aging
cardiovascular disease
angiogenesis
eNOS
Online Access:http://www.mdpi.com/1422-0067/19/10/3229

Internet

http://www.mdpi.com/1422-0067/19/10/3229

Similar Items