The cytoprotective role of DJ-1 and p45 NFE2 against human primary alveolar type II cell injury and emphysema

The cytoprotective role of DJ-1 and p45 NFE2 against human primary alveolar type II cell injury and emphysema

Abstract Emphysema is characterized by irreversibly enlarged airspaces and destruction of alveolar walls. One of the factors contributing to this disease pathogenesis is an elevation in extracellular matrix (ECM) degradation in the lung. Alveolar type II (ATII) cells produce and secrete pulmonary su...

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Bibliographic Details
Main Authors: Li Hui Tan, Karim Bahmed, Chih-Ru Lin, Nathaniel Marchetti, Sudhir Bolla, Gerard J. Criner, Steven Kelsen, Muniswamy Madesh, Beata Kosmider
Format: Article
Language:English
Published: Nature Publishing Group 2018-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-21790-3

Internet

https://doi.org/10.1038/s41598-018-21790-3

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