Mapping pathogenic processes contributing to neurodegeneration in Drosophila models of Alzheimer's disease

Mapping pathogenic processes contributing to neurodegeneration in Drosophila models of Alzheimer's disease

Alzheimer's disease (AD) is the most common form of dementia, affecting millions of people and currently lacking available disease‐modifying treatments. Appropriate disease models are necessary to investigate disease mechanisms and potential treatments. Drosophila melanogaster models of AD incl...

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Bibliographic Details
Main Authors: Liza Bergkvist, Zhen Du, Greta Elovsson, Hanna Appelqvist, Laura S. Itzhaki, Janet R. Kumita, Katarina Kågedal, Ann‐Christin Brorsson
Format: Article
Language:English
Published: Wiley 2020-03-01
Series:FEBS Open Bio
Subjects:
Alzheimer's disease
amyloid‐β
Drosophila melanogaster
endo‐lysosomal system
neurodegeneration
Online Access:https://doi.org/10.1002/2211-5463.12773

Internet

https://doi.org/10.1002/2211-5463.12773

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