Diffuse large B-cell lymphoma with concomitant c-MYC and BCL6 gene rearrangements with primary skin involvement: A case report and a review of literature

Diffuse large B-cell lymphoma with concomitant c-MYC and BCL6 gene rearrangements with primary skin involvement: A case report and a review of literature

Double-hit lymphoma (DHL) is a rare aggressive B-cell lymphoma with concomitant c-MYC, BCL2 or BCL6 gene rearrangements, which is characterized by the high frequency of extranodal lesions and by resistance to chemotherapy. The median survival does not exceed 18 months in patients with this disease....

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Bibliographic Details
Main Authors: N G Gabeeva, D A Koroleva, A V Belyaeva, N G Chernova, L A Kuzmina, A B Sudarikov, T N Obukhova, A M Kovrigina, E E Zvonkov, V G Savchenko
Format: Article
Language:Russian
Published: "Consilium Medicum" Publishing house 2017-07-01
Series:Терапевтический архив
Subjects:
double-hit lymphoma (dhl)
bcl2
bcl6
dlbcl leg-type
dhl
Online Access:https://ter-arkhiv.ru/0040-3660/article/viewFile/32297/pdf

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https://ter-arkhiv.ru/0040-3660/article/viewFile/32297/pdf

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