RT-SHIV subpopulation dynamics in infected macaques during anti-HIV therapy
<p>Abstract</p> <p>Background</p> <p>To study the dynamics of wild-type and drug-resistant HIV-1 RT variants, we developed a methodology that follows the fates of individual genomes over time within the viral quasispecies. Single genome sequences were obtained from 3 pi...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2009-11-01
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Series: | Retrovirology |
Online Access: | http://www.retrovirology.com/content/6/1/101 |