RT-SHIV subpopulation dynamics in infected macaques during anti-HIV therapy

<p>Abstract</p> <p>Background</p> <p>To study the dynamics of wild-type and drug-resistant HIV-1 RT variants, we developed a methodology that follows the fates of individual genomes over time within the viral quasispecies. Single genome sequences were obtained from 3 pi...

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Bibliographic Details
Main Authors: KewalRamani Vineet N, Lifson Jeffrey D, Stephens Robert M, Mellors John W, Maldarelli Frank, Kearney Mary, Shao Wei, Ambrose Zandrea, Coffin John M, Palmer Sarah E
Format: Article
Language:English
Published: BMC 2009-11-01
Series:Retrovirology
Online Access:http://www.retrovirology.com/content/6/1/101